London BioScience Innovation Centre
2 Royal College Street, London NW1 0NH
Intermediates & speciality chemicals synthesis & supply
Zenbiochem supplies high-purity fine chemicals for research, development, and commercial manufacture — from specialty reagents and building blocks to custom catalysts and ligands. Each batch is manufactured using environmentally responsible processes and released against full analytical specification with Certificate of Analysis, NMR, HPLC, and MS data.
Specialty building blocks
Unusual amino acids, heterocyclic fragments, fluorinated building blocks, and functionalised aromatic scaffolds for medicinal chemistry and drug discovery programs.
Catalysts & ligands
Phosphine ligands, N-heterocyclic carbene precursors, chiral catalysts, and transition-metal complexes — synthesised with low metal contamination and confirmed by elemental analysis.
Protecting group reagents
Boc-anhydride equivalents, Fmoc-OSu, CBz-Cl, silylating agents, and acylation reagents — supplied at high purity for reliable, reproducible protection chemistry.
Coupling reagents
HATU, HBTU, DIC, EDCI, COMU, and related amide bond-forming reagents manufactured to consistently high quality — critical for reproducible peptide and small molecule synthesis.
Analytical standards
Certified reference materials and analytical-grade standards for method development, instrument calibration, and regulatory submission impurity profiling at ≥99.5% purity.
Solvent & reagent kits
Custom solvent blends, buffer concentrates, and premixed reagent solutions formulated to your specification — supplied in ready-to-use formats for streamlined lab workflows.
Purity methods
HPLC-DAD (reverse-phase and normal-phase), GC-FID, Karl Fischer water determination, residue on ignition as appropriate per compound class.
Identity confirmation
¹H NMR, ¹³C NMR, HRMS/LRMS, IR. Elemental analysis available for metal-containing compounds. Chiral HPLC for ee determination.
Regulatory documentation
Certificate of Analysis (CoA), Safety Data Sheet (SDS/MSDS), and synthetic route summary. ICH Q7 guidelines followed for pharmaceutical-grade materials.
Packaging & storage
Supplied under inert atmosphere where required. Moisture-sensitive compounds packaged under argon with desiccant. Custom packaging specifications accommodated.
Batch reproducibility
Batch-to-batch consistency data available for ongoing supply agreements. Re-order matched to original batch specification unless otherwise agreed.
Supply scale
Gram quantities for research, 100 g–1 kg for development, kilogram+ for commercial manufacture. Long-term supply agreements available.
| Category | Example compounds | Purity grade | Typical scale |
|---|---|---|---|
| Coupling reagents | HATU, HBTU, DIC, COMU, Oxyma Pure | ≥99% | g – kg |
| Protecting group reagents | Fmoc-OSu, Boc₂O, Cbz-Cl, Alloc-Cl | ≥98% | g – kg |
| Chiral catalysts | Binap ligands, Salen complexes, cinchona alkaloid derivatives | ≥97% | mg – 100 g |
| Heterocyclic building blocks | Pyrimidine-carboxaldehydes, bromothiophenes, fluoropyridines | ≥99% | g – kg |
| Fluorinated reagents | DAST, Deoxofluor, SelectFluor equivalents | ≥97% | g – 100 g |
| Analytical standards | ICH impurity standards, metabolite references | ≥99.5% | mg – g |
Contact us with your specification — catalogue, custom, or ongoing supply requirements all welcomed.