Custom Synthesis — Approach — Zenbiochem
Custom Synthesis

Precision chemistry, built around your project

Zenbiochem delivers custom synthesis services across three specialised disciplines — small molecules, fine chemicals, and peptides. Every project is executed under our green chemistry framework: minimising solvent waste, avoiding hazardous reagents where alternatives exist, and delivering full analytical documentation as standard.

Whether you need a milligram reference standard, a gram-scale intermediate, or a kilogram API building block, our team designs the most efficient and environmentally responsible route to get you there.

Services — click to explore
Organic synthesis

Small Molecules Synthesis

Multi-step organic synthesis of pharmaceutical intermediates, building blocks, reference standards, and research compounds — from single-step transformations to complex chiral routes.

Fine chemicals

Intermediates & Speciality Chemicals

High-purity synthesis of reagents, catalysts, ligands, and specialty chemicals — produced under rigorous analytical quality control for consistent, reliable performance.

SPPS · Solution phase

Custom Peptide Synthesis

Custom peptides by solid-phase (SPPS) and solution-phase synthesis — standard sequences, difficult sequences, cyclic peptides, and side-chain modifications. From research-scale vials to GMP-ready batches.

How we work
Step 01

Enquiry & route assessment

Submit your target structure, desired purity, quantity, and timeline. We assess synthetic feasibility, identify green chemistry opportunities, and return a route proposal within 48 hours.

Route designFeasibility
Step 02

Quote & project agreement

Firm quote with milestones, timeline, and deliverables. We flag any regulatory, IP, or safety considerations at this stage and confirm analytical documentation requirements.

Fixed pricingMilestones
Step 03

Synthesis & QC

Execution under green chemistry principles. Intermediates and final product characterised by NMR, HPLC, MS, and IR/optical rotation as appropriate. Full batch documentation generated.

NMR / MS / HPLCCoA
Step 04

Delivery & documentation

Compound delivered with full Certificate of Analysis, Safety Data Sheet, and synthetic report. Regulatory files (DMF support, impurity profiles) available on request.

Full CoASDSRegulatory
Why Zenbiochem synthesis

Green chemistry by default

We evaluate every route against the 12 Principles of Green Chemistry — selecting atom-efficient reactions, renewable solvents, and catalytic alternatives to stoichiometric reagents wherever possible.

Full analytical characterisation

Every compound is characterised by NMR (¹H, ¹³C), HPLC purity, mass spectrometry, and additional techniques as required — with complete batch documentation supplied as standard.

Scalable from mg to kg

Routes are designed with scale in mind from the outset — so when you need to move from a milligram exploratory batch to kilogram commercial supply, we already have the process optimised.

Start your synthesis project today

Submit your target structure and requirements — we’ll respond with a route proposal within 48 hours.

ZenBiochem Limited · Custom Synthesis
London BioScience Innovation Centre · 2 Royal College Street, London NW1 0NH · info@zenbiochem.com
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